Freeze-Drying Technologies Enhance Process Development with Small Amounts of API

JoinSP Scientific and Dr. Alexandra Braun, of GILYOS GmbH, for an insightfulwebinar on miniaturization in freeze drying. Miniaturization is an importanttopic – especially in the early development phase of new drug entities – due tothe limited availability and costs of most Active Pharmaceutical Ingredients(API).

This webinar, which takes place on January 24 2019, will focus on ways tojumpstart your development effort, including the use of Manometric TemperatureMeasurement and SMART™ process analytical technology (PAT) tools in theLyoCapsule™ freeze dryer. Illustrated by several examples, Dr. Braun willdiscuss wall temperature adjustment, amorphous and crystalline formulations andminimum load requirements for reliable values. Dr Braun will also demonstratethe use of PAT tools in the development of a robust and reproducible cycle, aswell as the cycle transfer to larger units 

Theinnovative LyoCapsule™ consists of a small cylindrical inner-chamber intendedto freeze dry a reduced number of vials – typically seven x 20R vials. Itutilizes wall temperature control to emulate heat and mass transfer conditionstypically encountered in larger scale, and is equipped with a full suite of PATtools to facilitate process development and successful scale-up/scale-down.

To register for the “Miniaturization of Freeze Drying: Process Optimization inthe LyoCapsule™” webinar please visit contact SP Scientific at +1-845-255-5000 (+44-1473-240000 in Europe).

SP Scientific is a leading manufacturer of freeze dryers/lyophilizers, asepticequipment, temperature control/thermal management, centrifugal evaporators andconcentrators, glassware washers, and controlled environmental rooms andchambers. The company sells its products under well-known brands includingVirTis, Hull, PennTech, FTS Systems, Genevac and Hotpack. SP Scientific has ISO9001:2015 registered production facilities in the USA and Europe.