Fast High Throughput Protein Purification

Postnova Analytics has published an application report that describes a promising new protein purification technique based on diffusion.

Protein purification is a widely used and important tool for biotechnology labs. Traditionally the most commonly used techniques for protein purification have been based upon column chromatography, ultracentrifugation and ultrafiltration.

The applications report details the new analytical technique, developed by Postnova Analytics, which purifies proteins based upon their diffusion through a thin liquid barrier using a continuous SPLITT fractionation system.

Experimental results are provided that demonstrate how the diffusion-based purification system is able to provide a fast, high throughput alternative to traditional protein purification methods. A single cartridge continuous SPLITT fractionation system is shown to be capable of processing 1.4-litres of protein solution (43g of protein) per day.

Based on easily cleaned, reusable cartridges the continuous SPLITT fractionation system offers a cost effective and efficient tool for producing high purity proteins.

For a copy of this application report please visit https://www.postnova.com/application-note/view/59.html. For further information on Postnova Analytics’ new continuous SPLITT fractionation system contact the company on +49-8191-985-6880 / +44-1885-475007 / +1-801-521-2004 / [email protected].

Founded in 1997, Postnova Analytics is the inventor and leading international supplier of Field-Flow Fractionation (FFF) systems for markets including biopharmaceuticals, polymers, materials, nanotechnology and environmental sciences. Leveraging its unique and patented modular FFF – Light Scattering Platform, Postnova has been able to provide high performance solutions to a wide range of applications. Today the company’s growing product portfolio includes Flow FFF, Centrifugal FFF, Thermal FFF, Size Exclusion Chromatography (SEC), MALS and DLS Light Scattering.  Postnova (www.postnova.com) is located and headquartered in Landsberg am Lech (Germany) and has subsidiaries in the USA, UK and Finland. These offices, in conjunction with a highly qualified and trained distribution network, provide informed local support to customers worldwide.

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Worldwide HQ 

Postnova Analytics GmbH

Max-Planck-Straße 14
86899 Landsberg am Lech

Germany

 

Tel:     +49-8191-985-6880

Email: [email protected]
Web    www.postnova.com