How to improve the reproducibility of your flow chemistry

To enhance the reproducibility of flow chemistry scale-up – precise control of mixing and temperature in highly exothermic or rapid reactions is essential.

The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent.

Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C. GSM chips up to 2 ml can be operated up to 40-bar and are available in 2-channel or 3-channel inlet configurations.  Larger GSM chips of 10ml and 20 ml have a premixing channel followed by a residence domain and can operate up to 10-bar.

Glass Static Mixer chips can be used as mixing modules prior to a coil reactor residence time unit, or as reactor blocks for rapid exothermic reactions.

GSM chips from Uniqsis are precision machined from inert borosilicate glass to withstand a wide temperature range and can be conveniently attached to a FlowSyn column heater module, Cold Coil or Polar Bear Plus cryogenic reactor module.

For further information please visit  https://www.uniqsis.com/paProductsDetail.aspx?ID=ACC_CHIP or contact Uniqsis on +44-1223-942004 / [email protected]

Since 2007, Uniqsis has specialised in the design and supply of mesoscale continuous flow chemistry systems for a wide range of applications in chemical and pharmaceutical research. The company’s aim is to make flow chemistry easily accessible to both novices and experienced users.